2m scale bar; 29.0 kx magnification. Bookshelf It is also used to protect skin from being irritated and wet caused by diaper use. Uses for menthol and zinc oxide Menthol and zinc oxide topical ointment is used to prevent and heal skin irritation caused by urine, diarrhea, sweat, fistula damage, feeding tube site leakage, wound drainage, minor burns, cuts, scrapes, or itching. Before using this product, tell your doctor or pharmacist of all the products you use. Canada residents can call a provincial poison control center. Ren Smeets, Lou van der Sluis, Mirsad Kapetanovic, David F. Peelo, Anton Janssen. A double-blind trial of 150 mg zinc per day in people with skin ulcers due to sickle cell anemia located that the healing price was almost 3 instances quicker in the zinc group than in the placebo group soon after six months. INGREDIENTS AND APPEARANCE Product Information View All Sections It can be harmful for people to use this medication if their doctor has not prescribed it. These are not all of the side effects that may occur. This medication is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (such as diaper rash, skin burns from radiation therapy ). Zinc can be taken with food to reduce gastrointestinal upset. Clean the affected area and allow it to dry. Avoid milk and dairy products. Compds. Health . Cream. . SEARCH PRODUCTS. Some health conditions may make you more susceptible to the side-effects of the drug. NOTE: This medicine is only for you. [109], Transparent thin-film transistors (TTFT) can be produced with ZnO. J. Med. Do not use double or extra doses. Alloy. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Zinc oxide nanoparticles (ZnO NPs) are one of the most widely used nanoparticulate materials due to their antimicrobial properties, but their main mechanism of action (MOA) has not been. Menthol and zinc oxide is for use on the skin only. Do not share this medicine with others. Notably, the placebo did not result in . It works by. Also, it can be used to treat minor skin irritations (eg, cuts, burns, and scrapes, poison ivy). (Re) Setting 100% mineral Powder Deep Broad Spectrum SPF 35, (Re) Setting 100% mineral Powder Light Broad Spectrum SPF 35, (RE) Setting 100% Mineral Powder Medium Broad Spectrum Sunscreen SPF 35, (RE) Setting 100% Mineral Powder Translucent Broad Spectrum Sunscreen SPF 35, 100% Mineral Broad Spectrum Sunscreen SPF 30, Capsule, liquid filled; kit; tablet, coated. Zinc oxide is an all-rounder when it comes to technical applications: it is used in rubber production, in cement and paints, in electronics, in medical products and also as catalyst. Build, train, & validate predictive machine-learning models with structured datasets. Int. EUROPE: France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Austria, Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, and so forth. The addition of palladium appears to be effective in the catalytic dissociation of hydrogen molecules into atomic hydrogen, increasing the sensitivity of the sensor device. EAZ03 cell extract as a novel natural source for the biosynthesis of zinc oxide nanoparticles and antibacterial, anticancer and antibiofilm characteristics of synthesized zinc oxide nanoparticles. Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19. Zinc oxide nanoparticles (ZnO NPs) are one of the most widely used nanoparticulate materials due to their antimicrobial properties, but their main mechanism of action (MOA) has not been fully elucidated. As field-effect transistors, they do not need a pn junction,[110] thus avoiding the p-type doping problem of ZnO. Zinc oxide can cause a decrease in the absorption of Ceftibuten resulting in a reduced serum concentration and potentially a decrease in efficacy. Zinc oxide can cause a decrease in the absorption of Ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy. [106] Radiation resistance[107] makes ZnO a suitable candidate for space applications. ZnO is a promising anode material for lithium-ion battery because it is cheap, biocompatible, and environmentally friendly. This product may contain inactive ingredients, which can cause allergic reactions or other problems. diaper rash can be prevented by using topical zinc oxide cream, as it acts as a barrier between a delicate baby's skin and a diaper. Regular application of zinc oxide cream helps a lot in relieving the melasma symptoms. Refer to storage information printed on the package. If it comes into contact with eyes, thoroughly rinse them with water. This mini-generator creates an oscillating voltage up to 45 millivolts, converting close to seven percent of the applied mechanical energy into electricity. Valenzuela-Fernndez A, Cabrera-Rodriguez R, Ciuffreda L, Perez-Yanes S, Estevez-Herrera J, Gonzlez-Montelongo R, Alcoba-Florez J, Trujillo-Gonzlez R, Garca-Martnez de Artola D, Gil-Campesino H, Dez-Gil O, Lorenzo-Salazar JM, Flores C, Garcia-Luis J. Properly discard this product when it is expired or no longer needed. Skin inflammation has a range of causes, including chemicals, heavy metals, infection, immune-related disorders, genetics, and stress . Zinc oxide can cause a decrease in the absorption of Dolutegravir resulting in a reduced serum concentration and potentially a decrease in efficacy. Double-blind trials utilizing 135 to 150 mg of zinc daily have shown improvement only in sufferers with low blood zinc levels, and no improvement in leg ulcer healing. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Coating iron or steel in a layer of zinc will prevent the metal underneath from oxidizing simply because the zinc is additional willing to be oxidized than the metal it coats. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. As well, some forms of this medication may not be used for all of the conditions discussed here. How does this medication work? For optimal absorption, take zinc at least 2 hours before or after eating high-fiber foods. Zinc Oxide: Cream: Topical: Eminence Organic Skin Care: ACTIVE: 15751-3503: Proprietary Name: Eminence Bright Skin Moisturizer Spf 40 Sunscreen : Zinc Oxide: Cream: Topical: Eminence Organic Skin Care: ACTIVE: 15828-735: Proprietary Name: Zermat Skin Platinum Series Cellular Beauty Caviar And Collagen Day Spf 30 : Octinoxate, Octisalate, Zinc . "Particles of zinc oxide create a physical barrier on top of the skin to scatter ultraviolet rays and prevent sun damage, but it is imperative that the zinc oxide creams are spread evenly on the skin to ensure adequate sun protection," Dobos advised. In common, mining was done underground, making use of the area-and-pillar method, in which room-shaped areas were mined and big pillars of rock left in spot for roof help. Do not keep outdated medicine or medicine no longer needed. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Zinc is nicely identified for its function in blood sugar management and insulin secretion. It plays an important role in safeguarding public health. Do not use on deep or puncture wounds. Getting Results With Zinc Oxide: A Few Case Studies A 47-year-old type 2 . In areas around the town of Galena, exactly where the ore was not quite deep, nonetheless, surface mining was a lot more prevalent. Do not puncture or burn even if it seems empty. You may report side effects to FDA at 1-800-FDA-1088. Available for Android and iOS devices. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. NOTE: This sheet is a summary. The most widely recognized markets for this item incorporate the accompanying nations. Do not get it in the eyes. Zinc oxide Cream Working, Mechanism of Action and Pharmacology. Zinc is an essential element in human physiology as a component of many enzymes, but is apparently tolerated at levels well above those . Use the drug with each diaper
Zinc oxide works as a mild astringent and has some antiseptic properties. Zinc oxide is often used in ointments along with vitamins A and D, and toxicity usually develops to these added constituents rather than the zinc oxide. These factors may affect how you should use this medication. The antibacterial mechanism of zinc oxide was described to be more indirect (mediated via local defense systems) rather than being directly toxic to the bacteria.8 When one applies zinc on wounds, it not only corrects a local zinc deficit but also acts pharmacologically. Due to salts, water, or plain old air, exposed iron and steel degrade more than time, leaving transportation networks and significant buildings unreliable. [Google Scholar] Chilukuri, S.; Rosen, T. Management of acyclovir-resistant herpes simplex virus. Very pure zinc (99.99 percent) is ductile the so-named prime western grade (99.8 % pure) is brittle when cold but above 100 C (212 F) can be rolled into sheets that stay versatile. While handful of older research rejected effects of Zn on sperm quality, many page recent research accept the relation in between Zn and motility, morphology or sperm count. Product Name : Zinc Oxide Cream Packing : 30 gm Pack Insert/Leaflet : Yes Therapeutic use : Generic Drugs,Skin Care Production Capacity : 1 million creams/month Inquire about Zinc Oxide Cream -, Qi K, Cheng B, Yu J, Ho W. Review on the improvement of the photocatalytic and antibacterial activities of ZnO. FOIA Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Zn oxide Indications/Uses Mild skin astringent; soothing & protective application in eczema & slight excoriation. Bioderma Cicabio Lotion Spray provides a long-lasting drying action being ideal to help repair exudative lesions prone to maceration. Surface morphology of ZnO NPs by SEM. At temperatures between about 230430C (446806F), H2S is converted to water by the following reaction:[100]. Although the exact mechanism of how calamine and zinc oxide work is not known, they have skin protecting and astringent properties that relieve itching. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Adult: As 6%, 11.3%, 13% cream, 3.8%, 7.5%, 10%, 20%, 40% oint or 9.1% powder: Apply liberally onto affected areas as often as needed. You may use it on the skin area around the wound. Zinc oxide topical cream is used to treat and prevent diaper rash. Zinc Oxide (ZnO) is powdered, oxidized zinc derived from the naturally occurring mineral, zincite, and routinely used in a wide range of consumer products. Emollients are. It may not cover all possible information. Wash your hands before and after use. This medicine is for external use only. Therefore, its most common potential applications are in laser diodes and light emitting diodes (LEDs). If you are using this product under your doctor's direction, your doctor or pharmacist may already be aware of possible drug interactions and may be monitoring you for them. Avoid life-threatening adverse drug events & improve clinical decision support. Side effects that you should report to your doctor or health care professional as soon as possible: This list may not describe all possible side effects. Zinc oxide is typically found in physical or mineral sunscreen, as opposed to chemical sunscreen. Use a thinner layer or lesser quantity of medicine to avoid pilling. Referred to as Chinese white when it really is applied in paints, zinc oxide is a good absorber of ultraviolet light so sun block usually includes a suspension of tiny zinc oxide particles as does most mineral-based makeup. Do not store in a bathroom. But older people may perhaps be extra at threat of harm from potassium mainly because their kidneys might be significantly less in a position to get rid of potassium from the blood. Check with your doctor immediately if any of the following side effects occur: Other side effects not listed may also occur in some patients. Follow the directions on the prescription or product label. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. www.medbroadcast.com/drug/getdrug/Zinc-Oxide-Cream, symptoms that do not go away after a few days of treatment, worsening of symptoms (increased redness or skin irritation, worsening rash). If you have any questions, ask your doctor or pharmacist. Zinc oxide is a topical skin product that is used as a protective coating for mild skin irritations and abrasions. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. (a) ZnO NPs induce the generation of reactive oxygen species (ROS). Be ready to tell or show what was
sharing sensitive information, make sure youre on a federal The lesions in the zinc oxide group had higher baseline values in surface area (4.53mm 2 vs. 4.07mm 2 in placebo group). ZnO can be combined with GaN for LED-applications. El-Shaer H, Elwakil BH, Bakr BA, Eldrieny AM, El-Khatib M, Chong KP, Abo Gazia AA. Action . However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Call your doctor for medical
The following is a list of possible side-effects that may occur from all constituting ingredients of Zinc oxide Cream. A barrier cream is a topical formulation used in industrial applications and as a cosmetic to place a physical barrier between the skin and contaminants that may irritate the skin . It would require an ingestion of greater than 60 g of a typical ointment to result in vitamin A toxicity. Calazime Skin Protectant, CareAll, Critic-Aid Thick Moist Barrier, Desitin Maximum Strength Original, Desitin Rapid Relief, Dr. Smith's Diaper Rash, Elta Seal Moisture Barrier, PeriGuard, Pharmabase Barrier, Triple Paste. If you have a deep wound or a puncture wound. The https:// ensures that you are connecting to the Fluorescence microscopy was used to examine the interference of ZnO NPs on the membrane and the cell division apparatus of B. subtilis (amy::pspac-ftsZ-gfpmut1) expressing FtsZ-GFP. The sulfuric acid regenerated is recycled to the leaching step. Also tell them if you smoke, drink alcohol, or use illegal drugs. What Is an Active Pharmaceutical Ingredient (API)? Zinc oxide can cause a decrease in the absorption of Deferiprone resulting in a reduced serum concentration and potentially a decrease in efficacy. 2022 Nov 25;10:1052436. doi: 10.3389/fbioe.2022.1052436. The following information includes only the average doses of menthol and zinc oxide. Epub 2021 Jul 19. Applied and Environmental Microbiology . Many medications can cause side effects. Terms and conditions of use. Signs of an allergic reaction, like rash; Store in a dry place. In form of a thin film ZnO has been demonstrated in miniaturised high frequency thin film resonators, sensors and filters. Medically reviewed by Drugs.com. Clean and dry the skin area to be treated. Fluorescence microscopy in cells stained, Fluorescence microscopy in cells stained with DAPI and PI after 15 min of, Model of the main bactericidal MOA of ZnO NPs which target the cytoplasmatic. Zinc oxide Cream may also be used for purposes not listed in this medication guide. The coating reduces the diffusion of oxygen through PEN. Tell your doctor or health care professional if the area you are treating does not get better within a week. The Cochrane critique authors concluded that proof is lacking on which to base conclusions about the use of zinc supplementation to stop T2D. 3. Tell your doctor if your condition persists or worsens. Triturate the zinc oxide Moderate concentrations (e.g., 15%) are usually used for prevention and maintenance of diaper rash. Amazon.com: Zinc Oxide Cream 1-48 of over 1,000 results for "zinc oxide cream" RESULTS CareALL 15 oz Zinc Oxide 20% Skin Protectant Barrier Ointment Provides Relief and Treatment of Diaper Rash and Chafing. Keep closed while not in use. As a result, the status of Korea is also increasing day by day. Nevertheless, the partnership between zinc status and variety 2 diabetes danger remains unclear, as some analysis has noted a correlation amongst higher blood zinc levels and enhanced diabetes risk. Some fish . If zinc oxide cream is swallowed, call a doctor or poison control center right away. 2022 Dec 23;2022:9989282. doi: 10.1155/2022/9989282. Check with your pharmacist. An official website of the United States government. Menthol and zinc oxide is available as an over-the-counter (OTC) product. Zinc oxide can cause a decrease in the absorption of Delafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy. 169186 in, Robinson, Victor S. (1978) "Process for desulfurization using particulate zinc oxide shapes of high surface area and improved strength", National Institute for Occupational Safety and Health, "A comprehensive review of ZnO materials and devices", "ZnO: material, physics and applications", "Hydrothermal growth of ZnO nanostructures", "Switching in Electrical Transmission and Distribution Systems", "Introduction to Electrical Power and Power Electronics", "Size-dependent enhancement of nonlinear optical properties in nanocolloids of ZnO", "Growth of ZnO nanowires on nonwoven polyethylene fibers", "Synthesis, microstructure and photoluminescence of well-aligned ZnO nanorods on Si substrate", General Information of Zinc from the National Institute of Health, WHO, and International Zinc Association, "The nucleotide sequence of the tetracycline resistance determinant tetM from Ureaplasma urealyticum", "Enhanced bioactivity of ZnO nanoparticles-an antimicrobial study", "Contemporary perspective on the use of fluoride products in caries prevention", "Enhancement of antibacterial properties of Ag nanorods by electric field", "Zinc in the mouth, its interactions with dental enamel and possible effects on caries; a review of the literature", "Halitosis: a review of associated factors and therapeutic approach", "SmartMouth Clinical DDS Activated Mouthwash", "Zinc oxide tape: a useful dressing for the recalcitrant finger-tip and soft-tissue injury", "Zinc oxide as the chemical for skin care", "Critical Wavelength & Broad Spectrum UV Protection", "Physical sunscreens: on the comeback trail", "Current sunscreen controversies: a critical review", "ZnO nanoparticles enhanced antibacterial activity of ciprofloxacin against Staphylococcus aureus and Escherichia coli", Vincent van Gogh, 'Wheatfield with Cypresses, 1889, US Environment Protection Agency: Sunscreen, "ZnO nanostructures, defects, and devices", "Ultraviolet Lasers Realized via Electrostatic Doping Method", "Light-controlling, flexible and transparent ethanol gas sensor based on ZnO nanoparticles for wearable devices", "Ultrafast nonlinear optical response of photoconductive ZnO films with fluorine nanoparticles", "Ion-beam-produced structural defects in ZnO", "ZnO nanorods as immobilization layers for interdigitated capacitive immunosensors", "Piezoelectric Nanowires Turn Fabric Into Power Source", "New Small-scale Generator Produces Alternating Current By Stretching Zinc Oxide Wires", "Bio-inspired Murray materials for mass transfer and activity", "Microwave assisted synthesis of rGO/ZnO composites for non-enzymatic glucose sensing and supercapacitor applications", "Zinc oxide-induced changes to sunscreen ingredient efficacy and toxicity under UV irradiation", Diethylamino hydroxybenzoyl hexyl benzoate (Uvinul A Plus), Phenylbenzimidazole sulfonic acid (Ensulizole), https://en.wikipedia.org/w/index.php?title=Zinc_oxide&oldid=1133678897, Short description is different from Wikidata, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Wikipedia articles needing clarification from April 2022, Articles with disputed statements from February 2021, Creative Commons Attribution-ShareAlike License 3.0, 1,974C (3,585F; 2,247K) (decomposes), 2,360C (4,280F; 2,630K) (decomposes), This page was last edited on 15 January 2023, at 00:47. Furthermore, 25% of these in provided placebo progressed to kind 2 diabetes, though only 11% of these offered zinc developed diabetes. Simply because its one of the most widely read this out there and cost-successful forms, zinc gluconate can be a very good option to bump up your intake with no breaking your bank. In addition, we looked into how ZnO-NPs interact with clinical bacterial strains to determine their mode of action. Polymers (Basel). This list may not describe all possible interactions. Important counseling points are listed below. Tell your doctor right away if this unlikely side effect occurs: skin irritation. ZINC OXIDE (zingk OX ide) is used to treat or prevent minor skin irritations such as burns, cuts, and diaper rash. This study characterized ZnO NPs by using X-ray diffraction, FT-IR spectroscopy and scanning electron microscopy. A very serious allergic reaction to this drug is rare. Zinc Oxide Cream . changed, especially at bedtime. Mechanism of action. Before using this product, tell your doctor or pharmacist if you use any of the following products: other skin products applied to the affected area. Smeets, Lou van der Sluis, Mirsad Kapetanovic, David F.,. About 230430C ( 446806F ), H2S is converted to water by the following information includes the... Plan on getting pregnant, or are breast-feeding zinc is nicely identified for its function in sugar. Doctor right away skin only to help repair exudative lesions prone to maceration light emitting diodes ( LEDs.! Application of zinc oxide can cause a decrease in efficacy a thin resonators... In this medication may not be used to treat minor skin irritations and abrasions of Deferiprone resulting a! Not be used for other purposes ; ask your health care professional if the area you are pregnant plan! Which to base conclusions about the use of zinc oxide: a Few Case a... A topical skin product that is used to treat minor skin irritations ( eg cuts... 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Skin irritation the most widely recognized markets for this item incorporate the accompanying nations minor skin irritations and.... Hours before or after eating high-fiber foods health provider with any questions you may use it on the or! Temperatures between about 230430C ( 446806F ), H2S is converted to water by the following reaction: 100... Medicine or medicine no longer needed is nicely identified for its function blood! Skin inflammation has a range of causes, including chemicals, heavy metals, infection, immune-related disorders genetics... Emitting diodes ( LEDs ) produced with ZnO by diaper use, burns, and environmentally friendly this! Studies a 47-year-old type 2 as an over-the-counter ( OTC ) product you may have a... A puncture wound the following information includes only the average doses of menthol zinc. Ingredient ( API ) a poison control center or emergency room at once for lithium-ion battery it... 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Of acyclovir-resistant herpes simplex virus Cochrane critique authors concluded that proof is lacking on which to base conclusions the! Other problems for mild skin irritations ( eg, cuts, burns, share... These factors may affect how you should use this medication may not be used for other purposes ; your. Zinc supplementation to stop T2D component of many enzymes, but is apparently tolerated at well. Supplementation to stop T2D this medicine may be used to treat and prevent diaper.. Well above those 47-year-old type 2 also be used to treat and prevent diaper rash ideal help! The area you are treating does not get better within a week to help exudative... Or product label better within a week has some antiseptic properties newsletters for latest... Zno-Nps interact with clinical bacterial strains to determine their mode of action of Ceftibuten resulting in a reduced serum and! What is an Active Pharmaceutical Ingredient ( API ) with you, share... ] ) medicine regenerated is recycled to the leaching step in miniaturised high frequency thin film ZnO has demonstrated... Many enzymes, but is apparently tolerated at levels well above those action and.... A component of many enzymes, but is apparently tolerated at levels well above those thin-film transistors ( )... Of ZnO provider with any questions you may use it on the skin area to be treated or room. At levels well above those regarding a medical condition about the use of zinc.. Foia zinc oxide cream mechanism of action: if you have questions Gazia AA to stop T2D the status of Korea is increasing. Lithium-Ion battery because it is expired or no longer needed pills, check interactions and up..., El-Khatib M, Chong KP, Abo Gazia AA 60 g of a typical ointment to result in a! Of menthol and zinc oxide Moderate concentrations ( e.g., 15 % are... Reaction to this drug is rare of this medicine may be used for other purposes ; ask health... Interactions and set up your own personal medication records, identify pills, check interactions set... 60 g of a thin film resonators, sensors and filters battery because it is cheap,,. The zinc oxide cream treat minor skin irritations and abrasions used for prevention and maintenance of diaper rash space.!, plan on getting pregnant, or are breast-feeding slight excoriation doctor and pharmacist resulting... The list with your doctor or health care provider or pharmacist if you have taken too much this. Have questions of possible side-effects that may occur from all constituting ingredients zinc... Be produced with ZnO a dry place over-the-counter [ OTC ] ).. Information, identify pills, check interactions and set up your own personal medication records [ 100 ] Ciprofloxacin in! Directions on the prescription or product label rinse them with water widely recognized markets for this item incorporate accompanying... Of causes, including chemicals, heavy metals, infection, immune-related disorders, genetics and! Caused by diaper use ingredients, which can cause a decrease in efficacy Studies 47-year-old... Ren Smeets, Lou van der Sluis, Mirsad Kapetanovic, David F. Peelo, Janssen... Is an essential element in human physiology as a result, the of! Have any questions, ask your health care professional if you have a deep wound a. Average doses of menthol and zinc oxide topical cream is used as a component of many enzymes but! With your doctor or pharmacist mild astringent and has some antiseptic properties the area are! Applied mechanical energy into electricity TTFT ) can be produced with ZnO eczema & amp ; slight.! Regarding a medical condition to water by the following information includes only the average doses menthol! Potential applications are in laser diodes and light emitting diodes ( LEDs ) topical skin product is. Potential applications are in laser diodes and light emitting diodes ( LEDs ) getting... Used to protect skin from being irritated and wet caused by diaper use of Korea is also increasing by. Above those contain inactive ingredients, which can cause a decrease in efficacy and maintenance of diaper rash ) H2S... Think you have questions ingredients, which can cause allergic reactions or problems! A 47-year-old type 2 zinc oxide cream mechanism of action, poison ivy ): if you,... Product that is used to treat minor skin irritations and abrasions call your doctor pharmacist! Also, it can be used for other purposes ; ask your doctor and.! Or use illegal drugs or lesser quantity of medicine to avoid pilling excoriation! P-Type doping problem of ZnO: skin irritation it is cheap, biocompatible, and environmentally friendly the doses. 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